Propranolol and topical timolol for infantile haemangiomas of the skin
نویسندگان
چکیده
منابع مشابه
Propranolol for infantile haemangiomas: a review.
Infantile haemangiomas are the most common benign tumour of infancy. However the majority are self-resolving and only a small minority of cases require treatment, with various different medications being used in the past. Over the last few years, propranolol, a non-selective β-blocker, has become a popular and successful treatment for infantile haemangiomas. However, further research on its saf...
متن کاملPropranolol therapy for infantile haemangiomas: review of the literature.
OBJECTIVES Haemangiomas are the most common tumors of infancy affecting approximately 1 in 10 children. Unlike other tumors, haemangiomas enter an involution phase, during which they usually regress over the next several months to years. Sometimes intervention is required due to proliferative growth which is complicated by ulceration, bleeding, persistent aesthetic deformity or infection. MET...
متن کاملOral propranolol combined with topical timolol for compound infantile hemangiomas: a retrospective study
Compound infantile hemangiomas (IHs) are problematic and usually require intervention. This retrospective study aimed to introduce a combined therapy of oral propranolol and topical timolol, and evaluate its efficacy and safety. Eighty-nine infants with compound IHs were treated with oral propranolol 2 mg/kg/day divided 2 times per day and timolol maleate 0.5% gel 3 times per day, for at least ...
متن کاملTopical Timolol Maleate Treatment of Infantile Hemangiomas.
BACKGROUND There has been a dramatic increase in the off-label use of ophthalmic timolol maleate, a β-blocker used for infantile hemangioma (IH) treatment as a topical counterpart to oral propranolol. Its safety and efficacy in a pediatric population with IH have not been evaluated in a large cohort. Our goal was to retrospectively assess timolol's effectiveness, discern characteristics associa...
متن کاملTopical propranolol therapy for infantile hemangiomas.
The nonselective beta-adrenergic receptor antagonist propranolol is an effective therapy for infantile hemangiomas. Systemic propranolol therapy shows a rapid therapeutic effect with good drug tolerability. We report on the efficacy of local application of propranolol ointment in superficial hemangiomas of the skin. In our outpatient department, 45 children with 65 hemangiomas were treated with...
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ژورنال
عنوان ژورنال: Journal of Paediatrics and Child Health
سال: 2020
ISSN: 1034-4810,1440-1754
DOI: 10.1111/jpc.14730